High Efficiency Permanent Magnet Machine

The present invention is a high efficiency permanent magnet machine capable of maintaining high power density. The machine is operable over a wide range of power output. The improved efficiency is due in part to copper wires with a current density lower than traditional designs and larger permanent magnets coupled with a large air gap. In a certain embodiment wide stator teeth are used to provide additional improved efficiency through significantly reducing magnetic saturation resulting in lower current. The machine also has a much smaller torque angle than that in traditional design at rated load and thus has a higher overload handling capability and improved efficiency. In addition, when the machine is used as a motor, an adaptive phase lag compensation scheme helps the sensorless field oriented control (FOC) scheme to perform more accurately

Modeling of Breakdown-Limited Endurance in Spin-Transfer Torque Magnetic Memory under Pulsed Cycling Regime

Perpendicular spin-transfer torque (p-STT) magnetic memory is gaining increasing interest as a candidate for storage-class memory, embedded memory, and possible replacement of static/dynamic memory. All these applications require extended cycling endurance, which should be based on a solid understanding and accurate modeling of the endurance failure mechanisms in the p-STT device. This paper addresses cycling endurance of p-STT memory under pulsed electrical switching. We show that endurance is limited by the dielectric breakdown of the magnetic tunnel junction stack, and we model endurance lifetime by the physical mechanisms leading to dielectric breakdown. The model predicts STT endurance as a function of applied voltage, pulsewidth, pulse polarity, and delay time between applied pulses. The dependence of the endurance on sample area is finally discussed

Genetic epidemiology of motor neuron disease-associated variants in the Scottish population

Genetic understanding of motor neuron disease (MND) has evolved greatly in the past 10 years, including the recent identification of association between MND and variants in TBK1 and NEK1. Our aim was to determine the frequency of pathogenic variants in known MND genes and to assess whether variants in TBK1 and NEK1 contribute to the burden of MND in the Scottish population. SOD1, TARDBP, OPTN, TBK1, and NEK1 were sequenced in 441 cases and 400 controls. In addition to 44 cases known to carry a C9orf72 hexanucleotide repeat expansion, we identified 31 cases and 2 controls that carried a loss-of-function or pathogenic variant. Loss-of-function variants were found in TBK1 in 3 cases and no controls and, separately, in NEK1 in 3 cases and no controls. This study provides an accurate description of the genetic epidemiology of MND in Scotland and provides support for the contribution of both TBK1 and NEK1 to MND susceptibility in the Scottish population

Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias

We characterized the role of structural variants, a largely unexplored type of genetic variation, in two non-Alzheimer’s dementias, namely Lewy body dementia (LBD) and frontotemporal dementia (FTD)/amyotrophic lateral sclerosis (ALS). To do this, we applied an advanced structural variant calling pipeline (GATK-SV) to short-read whole-genome sequence data from 5,213 European-ancestry cases and 4,132 controls. We discovered, replicated, and validated a deletion in TPCN1 as a novel risk locus for LBD and detected the known structural variants at the C9orf72 and MAPT loci as associated with FTD/ALS. We also identified rare pathogenic structural variants in both LBD and FTD/ALS. Finally, we assembled a catalog of structural variants that can be mined for new insights into the pathogenesis of these understudied forms of dementia

Design, Analysis And Experiment Of A High Efficiency Permanent Magnet Truck Alternator

This paper presents the design and optimization of a high-efficiency permanent magnet synchronous alternator with the desired output power of 2 kW at 6 krpm applying to the truck power system. This kind of alternator requires low output voltage and high current. In order to effectively increase the overload power handing capability and efficiency of the designed alternator, the low torque angle is selected at the rated power and speed in the design. Key design methodologies and procedures are introduced and analyzed in detail. The corresponding finite element analysis (FEA) model is built. Structure optimization includes stator and rotor structure size, permanent magnet size, magnetic bridge and air gap length which are analyzed and simulated by ANSYS Maxwell 2D FEA. Thermal analysis is conducted, and the housing of alternator is designed. The alternator prototype is fabricated and tested based on our design. The simulation and test results verified the performance of the alternator